Datpalphas

Datpalphas

SCHEMBL222923

Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(O)(=S)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.76
ENPP1 P22413 6/20 0.70
P2RY1 P47900 5/20 0.70
P2RX1 P51575 3/20 0.59
P2RX3 P56373 3/20 0.59
P2RX2 Q9UBL9 2/20 0.59
P2RY11 Q96G91 2/20 0.59
DTYMK P23919 2/20 0.57
P2RY2 P41231 4/20 0.57
SRC P12931 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
P2RX4 Q99571 1/20 0.57
ALDH1A1 P00352 1/20 0.57
DNPH1 O43598 1/20 0.56
PRKAB2 O43741 1/20 0.56
TRPM2 O94759 1/20 0.56
LDHA P00338 1/20 0.56
ADRB2 P07550 1/20 0.56
FBP1 P09467 1/20 0.56
ADORA1 P30542 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Datpalphas SCHEMBL17117825 1.00 POLB (0.76) POLBENPP1P2RY1P2RX1P2RX3
Datpalphas SCHEMBL29507301 1.00 POLB (0.76) POLBENPP1P2RY1P2RX1P2RX3
Datpalphas SCHEMBL12836353 1.00 POLB (0.76) POLBENPP1P2RY1P2RX1P2RX3
Datpalphas SCHEMBL13049860 1.00 POLB (0.76) POLBENPP1P2RY1P2RX1P2RX3
SCHEMBL29352481 0.93 POLB (0.81) POLBENPP1P2RY1P2RX1P2RX3
SCHEMBL31211719 0.93 POLB (0.81) POLBENPP1P2RY1P2RX1P2RX3
Triphosphate SCHEMBL27892354 0.93 POLB (0.81) POLBENPP1P2RY1P2RX1P2RX3
SCHEMBL2508784 0.93 POLB (0.81) POLBENPP1P2RY1P2RX1P2RX3
SCHEMBL77641 0.93 POLB (0.81) POLBENPP1P2RY1P2RX1P2RX3
SCHEMBL5044161 0.92 POLB (0.80) POLBENPP1P2RY1P2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235939-A1 METHODS FOR BALANCED AMPLIFICATION OF SMALL SAMPLES OF NUCLEIC ACIDS ORCHID BIOSCIENCE, INC. (US) 2025-11-13 WO claimed
US-20250210148-A1 METHOD OF PRODUCING DATA-ENCODED NUCLEIC ACID AND NUCLEIC ACID PRODUCED BY THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-06-26 US claimed
US-20180355406-A1 POLYNUCLEIC ACID MOLECULE ENRICHMENT METHODOLOGIES GENETICS RESEARCH, LLC, D/B/A ZS GENETICS, INC. 2018-12-13 US claimed
US-20140170689-A1 Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-06-19 US claimed
US-20090023151-A1 Method For The Labeling And Detection Of Small Polynucleotides BIOVENTURES, INC. 2009-01-22 US claimed
EP-1192720-B1 ANCHORED STRAND DISPLACEMENT AMPLIFICATION ON AN ELECTRONICALLY ADDRESSABLE MICROCHIP NANOGEN BECTON DICKINSON PARTN (US) 2006-08-09 EP claimed
US-6864071-B2 Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification an bioelectronic chip technology NANOGEN/BECTON DICKINSON PARTNERSHIP (US) 2005-03-08 US claimed
US-6589742-B2 Producing single stranded amplicon species for detection, using asymmetrical amplification rather than heat or chemical denaturation NANOGEN, INC. 2003-07-08 US claimed
US-6531302-B1 Using primer pair sets anchored to a microarray through capture sites or through a branched primer pair moiety; allows for simultaneous multiplex capture, amplification, and detection of a target nucleic acid NANOGEN/BECTON DICKINSON PARTNERSHIP 2003-03-11 US claimed
US-6063604-A SEPARATION OF TARGET NUCLEOTIDE SEQUENCE FOUND WITHIN A SINGLE-STRANDED POLYNUCLEOTIDE; PROVIDING A REACTION MIXTURE, SEPARATING NUCLEOTIDE SEQUENCES, ALLOWING HYBRIDIZATION, PRIMER EXTENSION AND BREAKING, AMPLIFY NUCLEOTIDES MOLECULAR BIOLOGY RESOURCES, INC. (US) 2000-05-16 US claimed
US-5455166-A Genetic engineering BECTON, DICKINSON AND COMPANY (US) 1995-10-03 US claimed
US-4521509-A Method for degrading DNA RESEARCH CORPORATION (US) 1985-06-04 US claimed
US-20250361503-A1 DIRECTED EVOLUTION METHOD FOR TEMPLATE-INDEPENDENT POLYMERASES ANSA BIOTECHNOLOGIES INC (US) 2025-11-27 US disclosed
EP-3478853-B2 IMPROVEMENTS IN OR RELATING TO NUCLEIC ACID AMPLIFICATION PROCESSES LUMIRADX UK LTD (GB) 2025-11-26 EP disclosed
WO-2025235939-A1 METHODS FOR BALANCED AMPLIFICATION OF SMALL SAMPLES OF NUCLEIC ACIDS ORCHID BIOSCIENCE, INC. (US) 2025-11-13 WO disclosed
EP-4647507-A2 NUCLEIC ACID DETECTION METHOD Sense Biodetection Limited (GB) 2025-11-12 EP disclosed
US-5455166-A Genetic engineering BECTON, DICKINSON AND COMPANY (US) 1995-10-03 US disclosed
US-5270184-A Amplification BECTON, DICKINSON AND COMPANY (US) 1993-12-14 US disclosed
EP-0543612-A2 Nucleic acid target generation Becton, Dickinson and Company (US) 1993-05-26 EP disclosed
EP-0497272-A1 Strand displacement amplification Becton, Dickinson and Company (US) 1992-08-05 EP disclosed