Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15105951 | 0.81 | — | — | |
| SCHEMBL17174465 | 0.81 | — | — | |
| SCHEMBL165219 | 0.78 | CYP2C19 (0.34) | CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL5541231 | 0.78 | CYP2C19 (0.31) | CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL18548354 | 0.77 | CYP2C19 (0.56) | CYP2C19 | |
| SCHEMBL6245284 | 0.77 | — | — | |
| SCHEMBL19767 | 0.75 | CPB2 (0.35) | CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL15111139 | 0.75 | CYP2C19 (0.60) | CYP2C19 | |
| SCHEMBL31435809 | 0.74 | KCNA3 (0.33) | CYP2C19MEN1CYP2C9KMT2A | |
| SCHEMBL17162705 | 0.74 | POLB (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129392-B1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY, SUBSTITUTED IN POSITION 3 BY A NON-AROMATIC RING CARRYING A HALOALKYL SUBSTITUENT | VIIV HEALTHCARE UK NO 4 LTD (GB) | 2020-08-05 | — | — | EP | disclosed |