Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616570 | 0.87 | F11 (0.61) | F11 | |
| SCHEMBL616571 | 0.87 | F11 (0.61) | F11 | |
| SCHEMBL22294633 | 0.87 | F11 (0.60) | F11 | |
| SCHEMBL22294628 | 0.87 | F11 (0.57) | F11 | |
| SCHEMBL18059791 | 0.86 | F11 (0.69) | F11 | |
| SCHEMBL613199 | 0.86 | F11 (0.69) | F11 | |
| SCHEMBL613200 | 0.86 | F11 (0.69) | F11 | |
| SCHEMBL22294612 | 0.85 | F11 (0.62) | F11 | |
| SCHEMBL22294385 | 0.84 | F11 (0.72) | F11 | |
| SCHEMBL22294198 | 0.84 | F11 (0.79) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786165-A1 | SYNTHETIC INTERMEDIATES FOR PRODUCING MACROCYCLES AS FACTOR XIA INHIBITORS | Bristol-Myers Squibb Company (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-2534154-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-05 | — | — | EP | disclosed |