Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573964 | 0.96 | TDP1 (0.48) | TDP1TSHRCYP3A4HTTMEN1 | |
| SCHEMBL80455 | 0.96 | TDP1 (0.52) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL28729672 | 0.91 | TDP1 (0.53) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL17897871 | 0.91 | TDP1 (0.48) | TDP1HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL28728615 | 0.91 | TDP1 (0.53) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL431994 | 0.91 | TDP1 (0.53) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL429585 | 0.91 | TDP1 (0.53) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL230477 | 0.91 | TDP1 (0.53) | TDP1TSHRCYP3A4HTTLPAR1 | |
| SCHEMBL17111071 | 0.91 | TDP1 (0.42) | TDP1TSHRCYP3A4HTTMEN1 | |
| SCHEMBL4891281 | 0.89 | TDP1 (0.55) | TDP1TSHRCYP3A4HTTLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3463293-B1 | INJECTABLE SOLUTION AT PH 7, COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5, A PRANDIAL INSULIN AND/OR A GASTROINTESTINAL HORMONE, AND A COPOLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS | ADOCIA (FR) | 2021-05-12 | — | — | EP | disclosed |
| EP-3463294-B1 | COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION, COMPRISING HUMAN GLUCAGON AND A STATISTICAL COPOLYAMINO ACID | ADOCIA (FR) | 2020-08-05 | — | — | EP | disclosed |