Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229383 | 0.90 | GAA (0.42) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3966040 | 0.80 | POLB (0.60) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30806170 | 0.80 | MAPT (0.54) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10407866 | 0.79 | POLB (0.54) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL2343034 | 0.78 | MAPT (0.52) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10408718 | 0.77 | POLB (0.53) | POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3248990 | 0.77 | POLB (0.53) | POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5255929 | 0.77 | POLB (0.45) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10407954 | 0.77 | POLB (0.53) | POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL17307673 | 0.77 | POLB (0.45) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |