Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966040 | 0.85 | POLB (0.60) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28956628 | 0.85 | ALDH1A1 (0.40) | POLBALDH1A1MAPTGAAHTT | |
| SCHEMBL30806170 | 0.84 | MAPT (0.54) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10407866 | 0.83 | POLB (0.54) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL2343034 | 0.82 | MAPT (0.52) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3248990 | 0.81 | POLB (0.53) | POLBALDH1A1HTTCHRM2 | |
| SCHEMBL5255929 | 0.81 | POLB (0.45) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10408718 | 0.81 | POLB (0.53) | POLBALDH1A1HTTCHRM2 | |
| SCHEMBL10407954 | 0.81 | POLB (0.53) | POLBALDH1A1HTTCHRM2 | |
| SCHEMBL2917100 | 0.80 | POLB (0.50) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2023-08-10 | — | — | US | disclosed |
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| US-10033003-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-07-24 | — | — | US | disclosed |
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160133862-A1 | TETRADENTATE METAL COMPLEXES WITH CARBON GROUP BRIDGING LIGANDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160133862-A1 | TETRADENTATE METAL COMPLEXES WITH CARBON GROUP BRIDGING LIGANDS | STAU1, POLR1G, CLTC | POLB 390/4885HDAC3 2281/4885HDAC4 3909/4885 |
| US-10033003-B2 | Tetradentate metal complexes with carbon group bridging ligands | STAU1, POLR1G, CLTC | POLB 390/4885HDAC3 2281/4885HDAC4 3909/4885 |
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | POLB 390/4885HDAC3 2281/4885HDAC4 3909/4885 |
| US-20150349279-A1 | Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues | DPYD, DCTD, TYMP | POLB 179/4885HDAC3 2679/4885HDAC4 3450/4885 |
| US-11653560-B2 | Tetradentate metal complexes with carbon group bridging ligands | PDCD2L, STAU1, POLR1G | POLB 245/4885HDAC3 3345/4885HDAC4 3644/4885 |
| US-11839144-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | DPYD, DCTD, TYMP | POLB 179/4885HDAC3 2679/4885HDAC4 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.