Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595068 | 0.85 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1138627 | 0.84 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8863672 | 0.84 | TSHR (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5835078 | 0.82 | TSHR (0.35) | TSHRHPGD | |
| SCHEMBL27778925 | 0.82 | TSHR (0.35) | TSHRHPGD | |
| SCHEMBL28162731 | 0.81 | TSHR (0.34) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2921941 | 0.80 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11119332 | 0.80 | TSHR (0.33) | TSHRHPGDTHRB | |
| SCHEMBL27687881 | 0.80 | TSHR (0.33) | TSHRHPGD | |
| SCHEMBL28816507 | 0.79 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521752-B1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9493615-B2 | Organopolysiloxanes containing an unsaturated group | DOW CORNING CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2521752-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | Dow Corning Corporation (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20120283362-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW SILICONES CORPORATION | 2012-11-08 | — | — | US | disclosed |
| WO-2011083044-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083049-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING CORPORATION (US) | 2011-07-14 | — | — | WO | disclosed |