Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22295757 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22313920 | 0.86 | MAPT (0.32) | ALDH1A1MAPTNPSR1LMNAKMT2A | |
| SCHEMBL22313661 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22313635 | 0.83 | MAPT (0.42) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22313938 | 0.82 | POLB (0.39) | ALDH1A1KDM4EMAPTPKMLMNA | |
| SCHEMBL22314048 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22313954 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22295779 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTPKMNPSR1 | |
| SCHEMBL22295765 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTNPSR1LMNA | |
| SCHEMBL21160634 | 0.72 | MAPT (0.58) | ALDH1A1KDM4EMAPTKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3690002-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | East China University of Science and Technology (CN) | 2020-08-05 | — | — | EP | disclosed |