Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296387 | 1.00 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL22296389 | 1.00 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL21256945 | 0.84 | PIK3C3 (0.50) | PIK3C3 | |
| SCHEMBL26515061 | 0.84 | PIK3C3 (0.50) | PIK3C3 | |
| SCHEMBL24681530 | 0.83 | MTOR (0.50) | PIK3C3 | |
| SCHEMBL24681517 | 0.83 | MTOR (0.50) | PIK3C3 | |
| SCHEMBL25018626 | 0.83 | MTOR (0.50) | PIK3C3 | |
| SCHEMBL25222723 | 0.83 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL19863417 | 0.83 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL16611301 | 0.83 | PIK3C3 (0.49) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689871-B1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3689871-A1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |