Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296894 | 1.00 | OPRM1 (0.60) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL26638645 | 0.89 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL29808298 | 0.86 | OPRM1 (0.64) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL22283293 | 0.86 | OPRM1 (0.64) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL30288497 | 0.86 | OPRM1 (0.64) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL22261623 | 0.86 | OPRM1 (0.64) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL22296825 | 0.85 | OPRM1 (0.54) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL29967521 | 0.82 | OPRM1 (0.65) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL26638893 | 0.82 | OPRM1 (0.65) | OPRM1OPRD1OPRK1KCNH2SCN5A | |
| SCHEMBL30286713 | 0.81 | OPRM1 (0.70) | OPRM1OPRD1OPRK1KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265604-A1 | OXASPIRO SUBSTITUTED PYRROLOPYRAZOLE DERIVATIVE, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-10-25 | — | — | EP | disclosed |
| EP-3689859-A1 | METHOD FOR PREPARING OXASPIROCYCLE DERIVATIVE, AND INTERMEDIATE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |