Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.51 |
| ▸ | ITGAL | P20701 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362300 | 0.90 | ITGB2 (0.56) | NPC1ITGB2ICAM1ITGAL | |
| SCHEMBL18867795 | 0.83 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL13821875 | 0.83 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL17991453 | 0.83 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL13813600 | 0.82 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL13813573 | 0.80 | ITGB2 (0.50) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756039 | 0.80 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL19157817 | 0.80 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL23992594 | 0.79 | ITGB2 (0.47) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868524 | 0.76 | ITGB2 (0.53) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |