Tryptophan

Tryptophan

SCHEMBL2229691

CSCC[C@H](N)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.76

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.76
KDM4E B2RXH2 3/20 0.76
MAPT P10636 3/20 0.76
MEN1 O00255 3/20 0.76
LMNA P02545 2/20 0.76
TSHR P16473 2/20 0.76
BLM P54132 2/20 0.76
PMP22 Q01453 2/20 0.76
MPO P05164 1/20 0.76
HIF1A Q16665 1/20 0.76
CTSC P53634 3/20 0.66
APAF1 O14727 1/20 0.57
POLB P06746 1/20 0.57
RECQL P46063 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.55
HTR2A P28223 3/20 0.54
HTR1A P08908 2/20 0.54
HTR2C P28335 2/20 0.54
SLC6A4 P31645 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL23924440 1.00 KMT2A (0.76) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL11461241 1.00 KMT2A (0.76) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL2229687 1.00 KMT2A (0.76) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL8937030 0.96 KMT2A (0.70) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL3827133 0.96 KMT2A (0.70) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL23924534 0.96 KMT2A (0.70) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL27596671 0.94 KMT2A (0.67) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL7978131 0.93 KMT2A (0.65) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL7978129 0.93 KMT2A (0.65) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL3863016 0.93 KMT2A (0.65) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024131837-A1 ENGINEERED NUCLEASE WITH HIGH SALT TOLERANCE WUXI BIOLOGICS (SHANGHAI) CO., LTD. (CN) 2024-06-27 WO claimed
CN-117054657-B Combined blocking agent and application thereof in latex immunoturbidimetry detection 北京豪迈生物工程股份有限公司 2024-04-02 CN claimed
CN-117054657-A Combined blocking agent and application thereof in latex immunoturbidimetry detection 北京豪迈生物工程股份有限公司 2023-11-14 CN claimed
WO-2020069859-A1 SALT-FREE PREPARATION OF AMINO ACIDS FROM THEIR AMINO NITRILES EVONIK OPERATIONS GMBH (DE) 2020-04-09 WO claimed
WO-2020069862-A1 PREPARATION OF AMINO ACIDS FROM THEIR AMINO NITRILES EVONIK OPERATIONS GMBH (DE) 2020-04-09 WO claimed
EP-3632895-A1 SALT-FREE PRODUCTION OF AMINO ACIDS FROM THEIR AMINONITRILES Evonik Operations GmbH (DE) 2020-04-08 EP claimed
EP-3632896-A1 PRODUCTION OF AMINO ACIDS FROM THEIR AMINONITRILES Evonik Operations GmbH (DE) 2020-04-08 EP claimed
CN-108267580-A A kind of active group using specific dipeptides inhibits the immunoturbidimetry reagent of IgM types RF interference 南京天纵易康生物科技股份有限公司 2018-07-10 CN claimed
CN-107772117-A A kind of amino acid additive and its application in pig feed 宁波市远发生物工程有限公司 2018-03-09 CN claimed
US-20150183822-A1 ANGIOTENSIN-CONVERTING-ENZYME INHIBITING DIPEPTIDE YAMAKI CO., LTD. (JP) 2015-07-02 US claimed
CN-104583227-A Angiotensin-converting-enzyme inhibiting dipeptide YAMAKI CO LTD 2015-04-29 CN claimed
WO-2024131837-A1 ENGINEERED NUCLEASE WITH HIGH SALT TOLERANCE WUXI BIOLOGICS (SHANGHAI) CO., LTD. (CN) 2024-06-27 WO disclosed
CN-117054657-B Combined blocking agent and application thereof in latex immunoturbidimetry detection 北京豪迈生物工程股份有限公司 2024-04-02 CN disclosed
US-20240093248-A1 CELLS AND METHOD OF CELL CULTURE PFIZER INC. (US) 2024-03-21 US disclosed
CN-117054657-A Combined blocking agent and application thereof in latex immunoturbidimetry detection 北京豪迈生物工程股份有限公司 2023-11-14 CN disclosed
WO-1999009199-A2 ELONGATION FACTOR-2 KINASE (EF-2 KINASE) AND METHODS OF USE THEREFOR UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1999-02-25 WO disclosed
CN-1161001-A Lipid metabolism-improving agent KYOWA HAKKO KOGYO KK (JP) 1997-10-01 CN disclosed
US-5559142-A NUTRIENTS JAROWSKI CHARLES I (US) 1996-09-24 US disclosed
US-4235942-A LOW MOLECULAR WEIGHT POLYAMINO ACIDS FOR NUTRITIONAL FORTIFICATION STANDARD OIL COMPANY (INDIANA) (US) 1980-11-25 US disclosed
EP-0015668-A1 Digestible polyamino acids, method for preparing them and food fortified with the digestible polyamino acids Standard Oil Company (US) 1980-09-17 EP disclosed