Tryptophan

Tryptophan

SCHEMBL3863016

CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.65
MEN1 O00255 4/20 0.65
KDM4E B2RXH2 4/20 0.65
MAPT P10636 4/20 0.65
TSHR P16473 3/20 0.65
LMNA P02545 2/20 0.65
BLM P54132 2/20 0.65
PMP22 Q01453 2/20 0.65
MPO P05164 1/20 0.65
HIF1A Q16665 1/20 0.65
CTSC P53634 3/20 0.58
APAF1 O14727 1/20 0.53
POLB P06746 1/20 0.53
RECQL P46063 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
LTA4H P09960 1/20 0.50
PLA2G2A P14555 1/20 0.50
HTR1A P08908 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL8937030 0.97 KMT2A (0.70) KMT2AMEN1KDM4EMAPTTSHR
Tryptophan SCHEMBL3827133 0.97 KMT2A (0.70) KMT2AMEN1KDM4EMAPTTSHR
Dl-Tryptophan SCHEMBL11461241 0.93 KMT2A (0.76) KMT2AMEN1KDM4EMAPTTSHR
Dl-Tryptophan SCHEMBL2229687 0.93 KMT2A (0.76) KMT2AMEN1KDM4EMAPTTSHR
Tryptophan SCHEMBL2229691 0.93 KMT2A (0.76) KMT2AMEN1KDM4EMAPTTSHR
Dl-Tryptophan SCHEMBL23924440 0.93 KMT2A (0.76) KMT2AMEN1KDM4EMAPTTSHR
Dl-Tryptophan SCHEMBL27415496 0.92 KMT2A (0.63) KMT2AMEN1KDM4EMAPTTSHR
Tryptophan SCHEMBL9903583 0.92 MEN1 (0.55) KMT2AMEN1KDM4EMAPTTSHR
Tryptophan SCHEMBL294283 0.89 MEN1 (0.52) KMT2AMEN1KDM4EMAPTTSHR
Dl-Tryptophan SCHEMBL27596671 0.89 KMT2A (0.67) KMT2AMEN1KDM4EMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592160-B2 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2009-09-22 US disclosed
US-7241606-B2 α-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-07-10 US disclosed
US-7186701-B2 Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-03-06 US disclosed
US-20060240531-A1 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-10-26 US disclosed
US-20060008791-A1 Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-01-12 US disclosed