Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 1.00 |
| ▸ | HTR2B | P41595 | 19/20 | 1.00 |
| ▸ | HTR2A | P28223 | 16/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | HTR6 | P50406 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sb-243213 SCHEMBL31060820 | 0.87 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-243213 SCHEMBL677610 | 0.87 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-243213 SCHEMBL29697170 | 0.87 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-243213 SCHEMBL18321797 | 0.87 | HTR2C (0.98) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| SCHEMBL7078894 | 0.87 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-243213 SCHEMBL7473195 | 0.87 | HTR2C (0.98) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| SCHEMBL7082914 | 0.85 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| SCHEMBL7361498 | 0.84 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-242084 SCHEMBL507945 | 0.83 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 | |
| Sb-242084 SCHEMBL29462298 | 0.83 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP2C9HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091033-A1 | MODULATION OF NEUROGENESIS BY PPAR AGENTS | BRAINCELLS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |