Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22364516 | 1.00 | MTNR1A (0.61) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL21081149 | 0.86 | MTNR1A (0.58) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9470084 | 0.84 | MTNR1A (0.59) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL431801 | 0.84 | MTNR1A (0.56) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6445199 | 0.83 | MTNR1A (0.55) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL29058373 | 0.82 | MTNR1A (0.54) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL30395009 | 0.82 | MTNR1A (0.54) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL30395273 | 0.82 | MTNR1A (0.54) | MTNR1APOLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL10193173 | 0.81 | MTNR1A (0.46) | MTNR1A | |
| SCHEMBL19337132 | 0.81 | MTNR1A (0.46) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689860-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |