SCHEMBL22299079

SCHEMBL22299079

COOc1ccc2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.67
CYP1A2 P05177 2/20 0.67
AGXT P21549 2/20 0.54
TDP1 Q9NUW8 4/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 1/20 0.47
ALOX5 P09917 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NQO2 P16083 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
GAA P10253 1/20 0.44
RCE1 Q9Y256 1/20 0.44
GPR84 Q9NQS5 1/20 0.44
PTPN7 P35236 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3500443 0.87 CYP2A6 (0.67) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL112792 0.80 CYP1A2 (1.00) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL5311432 0.80 CYP1A2 (1.00) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL29353188 0.80 CYP1A2 (1.00) CYP2A6CYP1A2AGXTTDP1KDM4E
Water SCHEMBL17079094 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL11884025 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL27498364 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E
Methane SCHEMBL9286464 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E
Ethane SCHEMBL28740950 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E
Naphthalene SCHEMBL18344242 0.78 CYP1A2 (0.95) CYP2A6CYP1A2AGXTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020160377-A1 GAS SENSING IDENTIFICATION C2Sense, Inc. (US) 2020-08-06 WO disclosed