SCHEMBL3500443

SCHEMBL3500443

c1ccc2cc(OOc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.67
CYP1A2 P05177 3/20 0.67
AGXT P21549 2/20 0.65
TDP1 Q9NUW8 3/20 0.56
KDM4E B2RXH2 1/20 0.56
MAPK1 P28482 1/20 0.56
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
ALOX5 P09917 1/20 0.54
GAA P10253 1/20 0.52
RCE1 Q9Y256 1/20 0.52
GPR84 Q9NQS5 1/20 0.52
ALOX12 P18054 1/20 0.50
PTPN7 P35236 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22299079 0.87 CYP2A6 (0.67) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL395026 0.85 CYP1A2 (0.64) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL29366638 0.85 CYP1A2 (0.64) CYP2A6CYP1A2AGXTTDP1KDM4E
Hydrochloric Acid SCHEMBL9443225 0.82 CYP1A2 (0.61) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL29378143 0.82 CYP1A2 (0.61) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL28866254 0.82 AGXT (0.48) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL22109237 0.82 CYP2A6 (0.54) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL23742892 0.80 CYP1A2 (0.58) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL315704 0.80 CYP2A6 (0.58) CYP2A6CYP1A2AGXTTDP1KDM4E
SCHEMBL112792 0.80 CYP1A2 (1.00) CYP2A6CYP1A2AGXTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100133117-A1 METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-06-03 US disclosed
WO-2008097190-A1 METHODS OF ELECTRICALLY DETECTING A NUCLEIC ACID BY MEANS OF AN ELECTRODE PAIR AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-08-14 WO disclosed
WO-2008018833-A1 METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-02-14 WO disclosed