SCHEMBL22299138

SCHEMBL22299138

CCCCCCCCCC(=O)Nc1ccc(NCc2ccc(NC(C)=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.60
DGAT2 Q96PD7 1/20 0.60
HPGD P15428 1/20 0.56
PSMB11 A5LHX3 1/20 0.53
PSMA7 O14818 1/20 0.53
PSMB1 P20618 1/20 0.53
PSMA1 P25786 1/20 0.53
PSMA2 P25787 1/20 0.53
PSMA3 P25788 1/20 0.53
PSMA4 P25789 1/20 0.53
PSMB8 P28062 1/20 0.53
PSMB9 P28065 1/20 0.53
PSMA5 P28066 1/20 0.53
PSMB4 P28070 1/20 0.53
PSMB6 P28072 1/20 0.53
PSMB5 P28074 1/20 0.53
PSMB10 P40306 1/20 0.53
PSMB3 P49720 1/20 0.53
PSMB2 P49721 1/20 0.53
PSMA6 P60900 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22299144 1.00 ENPP2 (0.60) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299245 1.00 ENPP2 (0.60) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299119 0.89 PSMB11 (0.67) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299126 0.89 PSMB11 (0.67) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299128 0.89 PSMB11 (0.67) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299223 0.88 HDAC3 (0.59) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299135 0.88 ENPP2 (0.59) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299136 0.88 ENPP2 (0.59) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299234 0.88 ENPP2 (0.59) ENPP2DGAT2HPGDPSMB11PSMA7
SCHEMBL22299238 0.85 HPGD (0.74) ENPP2DGAT2HPGDPSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP claimed
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP disclosed
WO-2020157126-A1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF Università degli Studi di Salerno (IT) 2020-08-06 WO disclosed