Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1332486 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5403678 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1929377 | 1.00 | — | — | |
| Bicarbonate SCHEMBL83 | 1.00 | — | — | |
| Bicarbonate SCHEMBL15321596 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1332636 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9638573 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL10646323 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL8468228 | 0.94 | CA1 (0.56) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL9247593 | 0.94 | CA1 (0.56) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3509 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080091-A | Polyacid-based photoelectric functional material with reverse-light-conduction programmable switching characteristic, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122060000-A | Bimetallic heteronuclear complex and preparation method and application thereof | 武汉光化学技术研究院 | 2026-05-19 | — | — | CN | claimed |
| CN-122063209-A | Method for detecting hexavalent chromium in soil and sediment | 中煤浙江检测技术有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122042355-A | Pretreatment and detection method for measuring content of polycyclic aromatic hydrocarbon in biochar-based fertilizer | 江苏省农产品质量检验测试中心 | 2026-05-15 | — | — | CN | claimed |
| CN-122017222-A | Application of improved isoluminol luminous substrate in MaglumiX chemiluminescent immunoassay system | 浙江鑫科医疗科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-115881873-B | High-light-transmittance low-moisture-absorption material for LED packaging and preparation method thereof | 齐鲁工业大学(山东省科学院) | 2026-05-12 | — | — | CN | claimed |
| US-20260102388-A1 | COMPOUND SLOW-RELEASE IMPLANT OF NALTREXONE AND RISPERIDONE, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHENZHEN SCIENCARE PHARMACEUTICAL CO LTD (CN) | 2026-04-16 | — | — | US | claimed |
| EP-4585210-A1 | COMPOUND SLOW-RELEASE IMPLANT OF NALTREXONE AND RISPERIDONE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shenzhen Sciencare Pharmaceutical Co., Ltd. (CN) | 2025-07-16 | — | — | EP | claimed |
| CN-115896050-B | 7 Alpha-hydroxysteroid dehydrogenase terminal modification combining point mutation and efficient synthesis of ursodeoxycholic acid intermediate | 江南大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120192451-A | Styrene-acrylic emulsion for polymer cement waterproof mortar and preparation method and application thereof | 衡水新光新材料科技有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-1504192-A | Powder and injection preparation of pharmaceutical composition for curing organic phosphorus compound poisoning | 北京昭衍新药研究中心 | 2004-06-16 | — | — | CN | claimed |
| CN-1139811-C | Tumor early detection and evaluation kit and preparation process thereof | 赵永同 | 2004-02-25 | — | — | CN | claimed |
| US-6642185-B2 | Borate crosslinked fracturing fluid viscosity reduction breaker mechanism and products | BAKER HUGHES INCORPORATED | 2003-11-04 | — | — | US | claimed |
| CN-1361424-A | Enzyme immunoanalysis test kit for fast in-situ diagnosis of milk cow's early pregnancy and oestrus | GUO DAZHI (CN) | 2002-07-31 | — | — | CN | claimed |
| US-20020031526-A1 | Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2, 5-anhydro-D-mannose terminal structure and conjugate vaccine thereof | MICHON FRANCIS (US) | 2002-03-14 | — | — | US | claimed |
| US-6284884-B1 | DEPOLYMERIZATION AND REACTING WITH BASE TO FORM DE-N-ACETYLATED POLYSACCHARIDE; REACTING WITH NITROSATION AGENT | NORTH AMERICAN VACCINE, INC. | 2001-09-04 | — | — | US | claimed |
| EP-0830380-A1 | ANTIGENIC GROUP B STREPTOCOCCUS TYPE II AND TYPE III POLYSACCHARIDE FRAGMENTS HAVING A 2, 5-ANHYDRO-D-MANNOSE TERMINAL STRUCTURE AND CONJUGATE VACCINE THEREOF | NORTH AMERICAN VACCINE, INC. (CA) | 1998-03-25 | — | — | EP | claimed |
| US-5654156-A | PREPARING REAGENT COMPRISING LIPOSOMES CONTAINING ANTIGEN OR ANTIBODY WHICH BINDS ANALYTE TO BE MEASURED, ENCAPSULATING MARKER THEREIN, ACIDIFYING SAMPLE, CONTACTING SAMPLE WITH REAGENT, MEASURING AMOUNT OF DETECTABLE MARKER RELEASED | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | claimed |
| WO-1996040795-A1 | ANTIGENIC GROUP B STREPTOCOCCUS TYPE II AND TYPE III POLYSACCHARIDE FRAGMENTS HAVING A 2, 5-ANHYDRO-D-MANNOSE TERMINAL STRUCTURE AND CONJUGATE VACCINE THEREOF | NORTH AMERICAN VACCINE, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-4238420-A | Production of hexanitrostilbene using inorganic buffers | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1980-12-09 | — | — | US | claimed |