Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683328 | 0.80 | NPY5R (0.48) | TRPV1PDE2ANPY5R | |
| SCHEMBL22299102 | 0.74 | PPARG (0.46) | TRPV1FFAR1MCHR1 | |
| SCHEMBL22299211 | 0.74 | PPARG (0.46) | TRPV1FFAR1MCHR1 | |
| SCHEMBL13256564 | 0.73 | HTR2C (0.49) | TRPV1NPY5R | |
| SCHEMBL29500537 | 0.72 | KDM4E (0.44) | TRPV1GID4 | |
| SCHEMBL18537877 | 0.72 | KDM4E (0.44) | TRPV1GID4 | |
| Hydrochloric Acid SCHEMBL15310348 | 0.72 | HTR2C (0.50) | NPY5R | |
| Dimethylamine SCHEMBL16741892 | 0.72 | CYP2D6 (0.54) | TRPV1PDE2AMCHR1 | |
| Dimethylamine SCHEMBL16741899 | 0.71 | CYP2D6 (0.48) | PDE2AMCHR1 | |
| SCHEMBL13122212 | 0.71 | HDAC1 (0.54) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |