Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299211 | 1.00 | PPARG (0.46) | PPARGPPARAMCHR1NTRK1NTRK2 | |
| SCHEMBL2364109 | 0.81 | POLB (0.45) | — | |
| SCHEMBL28878992 | 0.75 | POLB (0.50) | — | |
| SCHEMBL22299409 | 0.74 | ADORA1 (0.43) | MCHR1FFAR1TRPV1 | |
| SCHEMBL11973911 | 0.73 | PDE10A (0.47) | NTRK1NTRK2TRPV1 | |
| SCHEMBL11904599 | 0.72 | PDE10A (0.47) | TRPV1 | |
| SCHEMBL8594366 | 0.71 | POLB (0.51) | — | |
| SCHEMBL12348255 | 0.71 | S1PR4 (0.49) | — | |
| SCHEMBL9721008 | 0.70 | KMT2A (0.60) | — | |
| SCHEMBL2679457 | 0.70 | KMT2A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |