Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDLR | P01130 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31577055 | 1.00 | LDLR (0.46) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL31576995 | 0.87 | AAK1 (0.47) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22288564 | 0.87 | AAK1 (0.47) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22298802 | 0.87 | KCNQ3 (0.47) | ALDH1A1SMN1; SMN2FFAR1KCNQ3KCNQ2 | |
| SCHEMBL31577161 | 0.87 | KCNQ3 (0.47) | ALDH1A1SMN1; SMN2FFAR1KCNQ3KCNQ2 | |
| SCHEMBL22299436 | 0.86 | LDLR (0.50) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22299453 | 0.86 | KCNQ3 (0.55) | FFAR1KCNQ3KCNQ2MCHR1 | |
| SCHEMBL31576865 | 0.86 | NPC1 (0.46) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22299445 | 0.86 | NPC1 (0.46) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22299432 | 0.84 | MCHR1 (0.45) | LDLRALDH1A1NPC1HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |