Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | LDLR | P01130 | 5/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576995 | 1.00 | AAK1 (0.47) | AAK1LDLRKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL31577159 | 0.94 | RORC (0.49) | AAK1LDLRKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL22299458 | 0.87 | LDLR (0.46) | LDLRKCNQ3KCNQ2ALDH1A1NPC1 | |
| SCHEMBL31577055 | 0.87 | LDLR (0.46) | LDLRKCNQ3KCNQ2ALDH1A1NPC1 | |
| SCHEMBL22299436 | 0.87 | LDLR (0.50) | LDLRALDH1A1NPC1HPGDNFKB1 | |
| SCHEMBL22299432 | 0.87 | MCHR1 (0.45) | LDLRKCNQ2ALDH1A1NPC1HPGD | |
| SCHEMBL31576948 | 0.87 | MCHR1 (0.45) | LDLRKCNQ2ALDH1A1NPC1HPGD | |
| SCHEMBL31576958 | 0.87 | MCHR1 (0.45) | LDLRKCNQ2ALDH1A1NPC1HPGD | |
| SCHEMBL22299362 | 0.86 | AAK1 (0.51) | AAK1LDLRKCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL22299431 | 0.84 | LDLR (0.45) | LDLRALDH1A1NPC1HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Universitá Degli Studi Di Salerno (IT) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |