Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.76 |
| ▸ | KDR | P35968 | 10/20 | 0.76 |
| ▸ | RET | P07949 | 4/20 | 0.76 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.76 |
| ▸ | GAK | O14976 | 1/20 | 0.76 |
| ▸ | STK10 | O94804 | 1/20 | 0.76 |
| ▸ | FLT3 | P36888 | 1/20 | 0.76 |
| ▸ | JAK3 | P52333 | 1/20 | 0.76 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.76 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.76 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.76 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.76 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.76 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 5/20 | 0.74 |
| ▸ | FLT1 | P17948 | 1/20 | 0.72 |
| ▸ | CLK1 | P49759 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.71 |
| ▸ | KIF5B | P33176 | 2/20 | 0.69 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Whi-P131 SCHEMBL29369589 | 0.86 | EGFR (1.00) | EGFRKDRRETRIPK2GAK | |
| Whi-P131 SCHEMBL29295 | 0.86 | EGFR (1.00) | EGFRKDRRETRIPK2GAK | |
| Whi-P131 SCHEMBL6068752 | 0.85 | EGFR (1.00) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL5473778 | 0.85 | EGFR (0.80) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL5467825 | 0.85 | EGFR (1.00) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL3533221 | 0.85 | EGFR (0.80) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL5472599 | 0.85 | EGFR (1.00) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL5485634 | 0.84 | KDM1A (0.76) | EGFRKDRRETRIPK2GAK | |
| SCHEMBL1387182 | 0.84 | EGFR (0.94) | EGFRKDRRETRIPK2GAK | |
| Hydrochloric Acid SCHEMBL5473795 | 0.84 | EGFR (0.80) | EGFRKDRRETRIPK2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160333-A1 | ENPP1 INHIBITORS AND METHODS OF MODULATING IMMUNE RESPONSE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |