Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418540 | 0.95 | APP (0.37) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22298999 | 0.91 | NR1H4 (0.38) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16265238 | 0.86 | CYP3A4 (0.36) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20806064 | 0.83 | NR1H4 (0.42) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17694318 | 0.82 | CYP3A4 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17835291 | 0.81 | APP (0.36) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2572427 | 0.79 | APP (0.48) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22238939 | 0.79 | RAB9A (0.51) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2671959 | 0.79 | CYP2D6 (0.50) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20647308 | 0.77 | SMN1; SMN2 (0.34) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020158038-A1 | LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL DIMMER ELEMENT | JNC株式会社 | 2020-08-06 | — | — | WO | disclosed |