SCHEMBL22299944

SCHEMBL22299944

CCOC(=O)c1ccc(/N=N/c2ccc(/N=N/c3ccc(/N=C/c4ccc(C)cc4O)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
GAA P10253 4/20 0.44
TP53 P04637 1/20 0.44
MAOB P27338 3/20 0.44
KDM4E B2RXH2 3/20 0.42
KMT2A Q03164 2/20 0.42
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAOA P21397 1/20 0.41
ALDH1A1 P00352 5/20 0.41
EGFR P00533 1/20 0.40
POLB P06746 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 2/20 0.38
LMNA P02545 2/20 0.38
HRH4 Q9H3N8 1/20 0.38
MEN1 O00255 1/20 0.38
DHODH Q02127 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22299217 0.88 MAPT (0.54) MAPTGAAKDM4EKMT2ARAB9A
SCHEMBL22299848 0.79 MAOB (0.43) MAPTGAAMAOBKDM4EKMT2A
SCHEMBL12070544 0.76 RAB9A (0.52) MAPTGAAKDM4EKMT2ARAB9A
SCHEMBL12071728 0.75 MAPT (0.55) MAPTKMT2ARAB9ANPC1L3MBTL1
SCHEMBL12069722 0.75 MAPT (0.55) MAPTKMT2ARAB9ANPC1L3MBTL1
SCHEMBL12767385 0.74 EGFR (0.61) MAPTGAAMAOBKDM4EKMT2A
SCHEMBL10817298 0.71 RAB9A (0.69) MAPTGAAKMT2ARAB9ANPC1
SCHEMBL22299849 0.71 MAOB (0.49) MAPTGAAMAOBKDM4EKMT2A
SCHEMBL12620662 0.70 MAPT (0.53) MAPTKDM4EKMT2ARAB9ANPC1
SCHEMBL11888418 0.70 RAB9A (0.67) MAPTGAAKMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020156832-A1 DICHROIC AZO-AZOMETHINE DYES FOR LIQUID CRYSTAL COMPOSITIONS BASF SE (DE) 2020-08-06 WO disclosed