Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299972 | 0.84 | ALB (0.54) | EPHX2SMN1; SMN2FOLH1ALDH1A1CA1 | |
| SCHEMBL18308654 | 0.82 | FOLH1 (0.51) | FOLH1ALDH1A1LMNA | |
| SCHEMBL23974245 | 0.80 | HDAC1 (0.38) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18307317 | 0.73 | FOLH1 (0.52) | FOLH1ALDH1A1LMNA | |
| SCHEMBL17190075 | 0.71 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL23720442 | 0.71 | FOLH1 (0.57) | FOLH1 | |
| SCHEMBL15739460 | 0.71 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL22135050 | 0.71 | EPHX2 (0.67) | EPHX2CASRKEAP1NFE2L2EPHX1 | |
| SCHEMBL18588225 | 0.70 | KDM4E (0.58) | SMN1; SMN2MAPK1TSHRFOLH1 | |
| SCHEMBL14930734 | 0.70 | KDM4E (0.58) | SMN1; SMN2MAPK1TSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |
| WO-2020156513-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | 同宜医药（苏州）有限公司 | 2020-08-06 | — | — | WO | disclosed |