SCHEMBL223

SCHEMBL223

N#Cc1ccccc1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.69
GABRG2 P18507 1/20 0.58
GABRB3 P28472 1/20 0.58
GABRA5 P31644 1/20 0.58
GABRA3 P34903 1/20 0.58
PTPN5 P54829 1/20 0.51
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
GALR3 O60755 1/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.46
TRPA1 O75762 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
FFAR1 O14842 1/20 0.44
AKR1B1 P15121 1/20 0.44
LRRK2 Q5S007 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29662886 1.00 ESR2 (0.69) ESR2GABRG2GABRB3GABRA5GABRA3
Water SCHEMBL3178714 1.00 ESR2 (0.69) ESR2GABRG2GABRB3GABRA5GABRA3
Bromide SCHEMBL27774142 0.98 ESR2 (0.67) ESR2GABRG2GABRB3GABRA5GABRA3
Hydrochloric Acid SCHEMBL6985442 0.98 ESR2 (0.67) ESR2GABRG2GABRB3GABRA5GABRA3
Methane SCHEMBL8312669 0.98 ESR2 (0.67) ESR2GABRG2GABRB3GABRA5GABRA3
Fluoride SCHEMBL27583847 0.98 ESR2 (0.67) ESR2GABRG2GABRB3GABRA5GABRA3
SCHEMBL2016996 0.95 ESR2 (0.70) ESR2GABRG2GABRB3GABRA5GABRA3
Ethylene SCHEMBL28042734 0.95 ESR2 (0.64) ESR2GABRG2GABRB3GABRA5GABRA3
SCHEMBL27895577 0.95 ESR2 (0.69) ESR2GABRG2GABRB3GABRA5GABRA3
Methylamine SCHEMBL3181738 0.93 ESR2 (0.62) ESR2GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7212 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079970-A Benzopentacyclic compound and application thereof 2026-05-26 CN claimed
CN-122060414-A Electric sensing paint, coating, preparation method, curing method and application 云南电网有限责任公司电力科学研究院 2026-05-19 CN claimed
CN-122010779-A Chiral binaphthol-cyano stilbene compound and preparation method and application thereof 蚌埠学院 2026-05-12 CN claimed
EP-4653941-A1 REVERSE MODE PDLC FILM HAVING HORIZONTAL ALIGNMENT OF LIQUID CRYSTALS, AND CONTINUOUS PROCESS MANUFACTURING EQUIPMENT AND METHOD FOR PDLC FILM COMPRISING ALIGNMENT LAYER Vsion Inc. (KR) 2025-11-26 EP claimed
US-20250279470-A1 CELLULOSIC-PROTEIN IONIC GEL, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME UNIVERSITY OF CONNECTICUT 2025-09-04 US claimed
CN-119987068-A Display module and display device 武汉华星光电技术有限公司 2025-05-13 CN claimed
CN-119960231-A Alignment method and application of cyanobiphenyl liquid crystal doped with organic donor material 齐鲁工业大学(山东省科学院) 2025-05-09 CN claimed
CN-119764572-A Modified novel electrolyte 合肥源元科技股份有限公司 2025-04-04 CN claimed
CN-119493307-A Alignment method and application of cyanobiphenyl liquid crystal doped with organic donor material 北华航天工业学院 2025-02-21 CN claimed
CN-119410379-A Squaraine double-line polarized fluorescent liquid crystal film and preparation method and application thereof 西安交通大学 2025-02-11 CN claimed
US-4309304-A AROMATIC NITRILES AND ESTERS EXXON RESEARCH & ENGINEERING CO. (US) 1982-01-05 US claimed
EP-0032397-A1 Method of manufacturing a liquid crystal display SIEMENS AKTIENGESELLSCHAFT (DE) 1981-07-22 EP claimed
EP-0028519-A1 Liquid crystal compositions for multiplexed displays MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-05-13 EP claimed
EP-0028520-A1 Improved liquid crystal compositions for multiplexed displays MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-05-13 EP claimed
US-4261651-A CYCLOHEXANE CONTAINING DERIVATIVES OF AROMATIC NITRILES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1981-04-14 US claimed
US-4253740-A AT LEAST THREE COMPOUNDS, TWO OF WHICH ARE BIPHENYL MONONITRILES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1981-03-03 US claimed
US-4165922-A Liquid crystal cell INTERNATIONAL STANDARD ELECTRIC CORPORATION (US) 1979-08-28 US claimed
US-4145114-A LIQUID CRYSTALS, AZO DYES, ELECTROOPTICAL DEVICE THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1979-03-20 US claimed
US-4019996-A CONTAINING MONOCYANO-PHENOXYBENZENE, -DIPHENYL OR -TERPHENYL IN A LIQUID RHONE-POULENC INDUSTRIES (FR) 1977-04-26 US claimed
US-4011046-A LIQUID CRYSTAL QUANTITATIVE ANALYSIS METHOD FOR OPTICALLY ACTIVE COMPOUNDS TEMPLE UNIVERSITY (US) 1977-03-08 US claimed