Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064294 | 0.84 | CPN1 (0.49) | CPN1CPB2CTSKALOX15ANPEP | |
| SCHEMBL4234207 | 0.77 | CPN1 (0.47) | CPN1CPB2ALOX15ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL6229687 | 0.75 | CPN1 (0.46) | CPN1CPB2ALOX15ANPEPERAP2 | |
| SCHEMBL4491138 | 0.73 | ITGB3 (0.42) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27819298 | 0.72 | CPN1 (0.44) | CPN1CPB2CTSKALOX15ANPEP | |
| SCHEMBL1797700 | 0.71 | CPN1 (0.49) | CPN1CPB2ALOX15ANPEPERAP2 | |
| SCHEMBL1797702 | 0.71 | CPN1 (0.49) | CPN1CPB2ALOX15ANPEPERAP2 | |
| SCHEMBL21334736 | 0.71 | CPN1 (0.58) | CPN1CPB2ALOX15ITGB3ITGA2B | |
| SCHEMBL13406394 | 0.71 | CPN1 (0.58) | CPN1CPB2ALOX15ITGB3ITGA2B | |
| SCHEMBL6189242 | 0.70 | CPN1 (0.53) | CPN1CPB2ALOX15ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160333-A1 | ENPP1 INHIBITORS AND METHODS OF MODULATING IMMUNE RESPONSE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |