Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092688 | 0.93 | HRH3 (0.42) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL24870608 | 0.89 | HRH3 (0.44) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL22456360 | 0.89 | L3MBTL3 (0.42) | HRH3L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| SCHEMBL10162401 | 0.88 | L3MBTL3 (0.44) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3439846 | 0.88 | L3MBTL3 (0.48) | HRH3L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| SCHEMBL25050072 | 0.87 | L3MBTL3 (0.44) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL24742908 | 0.87 | HRH3 (0.47) | HRH3 | |
| SCHEMBL8263855 | 0.86 | L3MBTL3 (0.47) | HRH3L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| SCHEMBL278657 | 0.86 | L3MBTL3 (0.47) | HRH3L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| SCHEMBL8255448 | 0.86 | L3MBTL3 (0.47) | HRH3L3MBTL3L3MBTL1MBTD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160193-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |