Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193387 | 0.98 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22300822 | 0.98 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL23446645 | 0.97 | LMNA (0.47) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22193388 | 0.95 | MEN1 (0.42) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL24084105 | 0.95 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL23463323 | 0.94 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL24084051 | 0.93 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL23447554 | 0.93 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDTLR2 | |
| SCHEMBL23463322 | 0.93 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL23446284 | 0.93 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919080-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2021109351-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| WO-2021103342-A1 | POLYETHYLENE GLYCOL CONJUGATED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| WO-2020155497-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2020-08-06 | — | — | WO | disclosed |