Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490413 | 0.97 | TYMP (0.37) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL22301452 | 0.97 | TYMP (0.39) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL18490433 | 0.96 | KDM4E (0.38) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL27216196 | 0.93 | KDM4E (0.38) | TYMPKDM4EPRMT6GAPDH | |
| SCHEMBL20474396 | 0.92 | TYMP (0.39) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL18490321 | 0.92 | TYMP (0.39) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| Pyridine SCHEMBL22034362 | 0.92 | TYMP (0.34) | TYMPKDM4E | |
| SCHEMBL22301451 | 0.91 | TYMP (0.38) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL20248733 | 0.90 | TYMP (0.35) | TYMPKDM4EPRMT6GAPDHTAS1R3 | |
| SCHEMBL18992202 | 0.90 | TYMP (0.38) | TYMPKDM4EPRMT6GAPDHTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | STING1, CGAS, IFNAR1 | TYMP 1396/4885KDM4E 3981/4885PRMT6 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.