SCHEMBL2230148

SCHEMBL2230148

CCN1CCCC1=O.COCCOCCOC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.44
TSHR P16473 2/20 0.40
CHRM2 P08172 3/20 0.38
CHRM5 P08912 3/20 0.38
CHRM1 P11229 3/20 0.38
CHRM3 P20309 3/20 0.38
CYP2D6 P10635 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
APEX1 P27695 2/20 0.38
PMP22 Q01453 2/20 0.38
ALOX12 P18054 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
INMT O95050 1/20 0.38
CYP1A2 P05177 1/20 0.38
CHRM4 P08173 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ACACB O00763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28319486 0.86 KMT2A (0.44) PIK3CDTSHRKMT2A
SCHEMBL19514136 0.86 PIK3CD (0.44) PIK3CDTSHRCHRM2CHRM5CHRM1
Di(Hydroxyethyl)Ether SCHEMBL2230146 0.83 PIK3CD (0.42) PIK3CDTSHRCHRM2CHRM5CHRM1
SCHEMBL18635 0.83
SCHEMBL27958225 0.83 PIK3CD (0.59) PIK3CDTSHRCHRM2CHRM5CHRM1
Hydrochloric Acid SCHEMBL23248746 0.81
Water SCHEMBL6122968 0.81 PIK3CD (0.57) PIK3CDTSHRCHRM2CHRM5CHRM1
Arsenic SCHEMBL28843817 0.81
Water SCHEMBL6122410 0.81
SCHEMBL30679684 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011089090-A1 URETHANIZED POLYESTERS BAYER MATERIALSCIENCE AG (DE) 2011-07-28 WO disclosed