⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769356 | 0.70 | — | — | |
| SCHEMBL12197844 | 0.70 | — | — | |
| SCHEMBL24125960 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL7907972 | 0.65 | CHRM1 (0.35) | — | |
| SCHEMBL25530181 | 0.65 | — | — | |
| SCHEMBL27089756 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL22984864 | 0.64 | KDM4E (0.33) | — | |
| SCHEMBL13233726 | 0.64 | CYP2D6 (0.33) | — | |
| SCHEMBL23033204 | 0.64 | HRH3 (0.36) | — | |
| SCHEMBL24250661 | 0.64 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020160193-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020160198-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |