Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737187 | 0.89 | — | — | |
| SCHEMBL18592713 | 0.85 | CYP2D6 (0.35) | CHRNA7HRH3 | |
| SCHEMBL9963122 | 0.85 | CYP2D6 (0.35) | CHRNA7HRH3 | |
| SCHEMBL18592719 | 0.85 | CYP2D6 (0.35) | CHRNA7HRH3 | |
| SCHEMBL4550439 | 0.81 | — | — | |
| SCHEMBL18592715 | 0.81 | — | — | |
| SCHEMBL18592720 | 0.81 | — | — | |
| SCHEMBL24125960 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1MAPTPKMCHRNA7 | |
| SCHEMBL23380854 | 0.77 | OPRM1 (0.36) | KDM4EALDH1A1MAPTPKMCHRNA7 | |
| SCHEMBL25081786 | 0.77 | HRH3 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | KDM4E 4848/4885ALDH1A1 4861/4885MAPT 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.