Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464754 | 0.79 | CRBN (0.41) | CRBNDDB1IKZF3TDP1KMT2A | |
| SCHEMBL29314083 | 0.73 | CRBN (0.43) | CRBNDDB1IKZF3TDP1ALDH1A1 | |
| SCHEMBL23561213 | 0.73 | CRBN (0.61) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL22006012 | 0.73 | CRBN (0.41) | CRBNDDB1IKZF3TDP1ALDH1A1 | |
| SCHEMBL21477243 | 0.73 | CRBN (0.51) | CRBNDDB1IKZF3TDP1ALDH1A1 | |
| SCHEMBL22307191 | 0.71 | CRBN (0.61) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL21464478 | 0.71 | CRBN (0.41) | CRBNDDB1IKZF3 | |
| SCHEMBL21464665 | 0.70 | CRBN (0.38) | CRBNDDB1IKZF3LMNATDP1 | |
| SCHEMBL20046865 | 0.68 | CRBN (0.47) | CRBNDDB1IKZF3TDP1ALDH1A1 | |
| SCHEMBL22150334 | 0.68 | CRBN (0.51) | CRBNDDB1IKZF3L3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160193-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |