Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.61 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23561213 | 0.93 | CRBN (0.61) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL27290606 | 0.85 | CRBN (0.59) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL30484267 | 0.84 | CRBN (0.57) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL26456733 | 0.84 | CRBN (0.57) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL30042984 | 0.83 | CRBN (0.72) | CRBNCSNK1A1MAP1LC3B | |
| SCHEMBL27099036 | 0.83 | CRBN (0.58) | CRBNIKZF3CSNK1A1MAP1LC3BIKZF2 | |
| SCHEMBL26739474 | 0.82 | CRBN (0.57) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL26739443 | 0.82 | CRBN (0.55) | CRBNIKZF3CSNK1A1MAP1LC3BDDB1 | |
| SCHEMBL30373201 | 0.82 | CRBN (0.55) | CRBNIKZF3CSNK1A1MAP1LC3BIKZF2 | |
| SCHEMBL26091035 | 0.81 | CRBN (0.67) | CRBNCSNK1A1GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160196-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |