SCHEMBL2230263

SCHEMBL2230263

Cc1ccccc1C(=O)c1cccc(C)c1C(=O)c1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
KMT2A Q03164 1/20 0.50
HPGD P15428 2/20 0.44
MYC P01106 1/20 0.44
MAPK13 O15264 3/20 0.44
MAPK12 P53778 3/20 0.44
MAPK11 Q15759 3/20 0.44
MAPK14 Q16539 3/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
ENPP3 O14638 1/20 0.42
ALPL P05186 1/20 0.42
XIAP P98170 1/20 0.42
BCHE P06276 1/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7041793 0.91 CYP3A4 (0.48) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL16168317 0.88 CYP3A4 (0.61) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL29387256 0.87 CYP3A4 (0.55) CYP3A4CYP2C9KMT2AHPGDMAPK13
SCHEMBL333141 0.87 CYP3A4 (0.55) CYP3A4CYP2C9KMT2AHPGDMAPK13
SCHEMBL10951938 0.85 KMT2A (0.45) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL19712126 0.85 KMT2A (0.42) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL10669335 0.84 CYP3A4 (0.59) CYP3A4CYP2C9KMT2AHPGDMAPK13
SCHEMBL5713104 0.83 ALDH1A1 (0.44) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL6911949 0.83 MYC (0.50) CYP3A4CYP2C9KMT2AHPGDMYC
SCHEMBL4019723 0.82 MAPK13 (0.51) CYP3A4CYP2C9KMT2AHPGDMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461270-B2 Olefin/aromatic vinyl copolymer, process for production thereof, resin compositions containing the copolymer, and stretched products of the copolymer IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
US-20110172366-A1 OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER IDEMITSU KOSAN CO., LTD. (JP) 2011-07-14 US disclosed