Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560724 | 0.71 | USP2 (0.39) | TSHRKMT2AALDH1A1HDAC4 | |
| SCHEMBL22285654 | 0.71 | PTPN5 (0.46) | KMT2AMEN1ALDH1A1RXFP1 | |
| SCHEMBL25071330 | 0.70 | POLB (0.43) | KMT2AHDAC6MLYCDMEN1NPC1 | |
| SCHEMBL25071689 | 0.69 | NPC1 (0.42) | HDAC6OPRK1OPRD1MLYCDALDH1A1 | |
| SCHEMBL10453342 | 0.69 | TSHR (0.47) | TSHRKMT2AHDAC6MEN1ALDH1A1 | |
| Lithium Ion SCHEMBL30953330 | 0.69 | PTPN5 (0.43) | KMT2AMEN1ALDH1A1RXFP1 | |
| SCHEMBL5755397 | 0.68 | NOTUM (0.44) | TSHRKMT2AMEN1NPC1NAMPT | |
| SCHEMBL3379859 | 0.67 | HDAC6 (0.55) | KMT2AHDAC6OPRK1MLYCDMEN1 | |
| SCHEMBL4400995 | 0.67 | MEN1 (0.52) | KMT2AHDAC6MEN1NAMPT | |
| SCHEMBL4245335 | 0.66 | CHRM3 (0.45) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247785-A1 | IL-17 Ligands And Uses Thereof | DICE MOLECULES SV, INC. | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247785-A1 | IL-17 Ligands And Uses Thereof | IL17A, IL2, IL15 | TSHR 1882/4885KMT2A 4343/4885HDAC6 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.