SCHEMBL2230430

SCHEMBL2230430

CCC(C)CO[SiH](CCl)OCC(C)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27919761 0.77
SCHEMBL10350312 0.76 MAPT (0.35) MAPT
SCHEMBL27802898 0.75
SCHEMBL29318038 0.74
SCHEMBL11417689 0.71 LMNA (0.36)
SCHEMBL319955 0.69
SCHEMBL28758589 0.67
SCHEMBL11925999 0.67
SCHEMBL13939091 0.67
SCHEMBL2037327 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP claimed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US claimed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP claimed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US claimed
EP-1721930-B1 RUBBER COMPOSITION JSR CORP (JP) 2015-01-28 EP disclosed
US-7981966-B2 Rubber composition JSR CORPORATION (JP) 2011-07-19 US disclosed
US-20070185267-A1 Rubber composition JSR CORPORATION (JP) 2007-08-09 US disclosed
EP-1721930-A1 RUBBER COMPOSITION JSR Corporation (JP) 2006-11-15 EP disclosed
EP-1205506-B1 Rubber composition and methods for producing the same JSR CORP (JP) 2004-12-29 EP disclosed
EP-0992537-B1 Oil extended rubber and rubber composition JSR CORP (JP) 2004-12-29 EP disclosed
US-6740700-B2 KNEADING FORMULATION COMPRISING A RUBBER COMPONENT CONTAINING CONJUGATED DIENE-BASED RUBBER AND A SILICA; KNEADING SILANE COUPLING AGENT AND FIRST RUBBER, KNEADING SECOND RUBBER FORMULATION, ZINC OXIDE AND VULCANIZING AGENT JSR CORPORATION (JP) 2004-05-25 US disclosed
EP-1000970-B1 Polymodal conjugated diolefin vinyl aromate rubber composition JSR CORP (JP) 2003-05-02 EP disclosed
US-6344518-B1 Conjugated diolefin copolymer rubber and rubber composition JSR CORPORATION (JP) 2002-02-05 US disclosed
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP disclosed
EP-1000970-A1 Polymodal conjugated diolefin vinyl aromate rubber composition JSR Corporation (JP) 2000-05-17 EP disclosed
EP-0992537-A1 Oil extended rubber and rubber composition JSR Corporation (JP) 2000-04-12 EP disclosed
US-5496883-A COMPRISING TREAD RUBBER OF POLYBUTADIENE POLYMER OR COPOLYMER CONTAINING SILICA AND MODIFIED WITH SILANE COUPLING AGENT; COUPLING AGENT; WET SKID RESISTANCE, LOW ROLLLING RESISTANCE BRIDGESTONE CORPORATION (JP) 1996-03-05 US disclosed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US disclosed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP disclosed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US disclosed