SCHEMBL2230433

SCHEMBL2230433

CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.CCCCCCCCC[n+]1ccc(C)cc1.O=P([O-])([O-])F.O=P([O-])([O-])F.O=P([O-])([O-])F.O=P([O-])([O-])F.O=P([O-])([O-])F.O=P([O-])([O-])F

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.73
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
MAPT P10636 2/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 2/20 0.53
KDM4E B2RXH2 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
HSP90AA1 P07900 3/20 0.47
MAPK1 P28482 2/20 0.47
APAF1 O14727 1/20 0.47
RGS12 O14924 1/20 0.47
CHRM2 P08172 2/20 0.47
ADRA2A P08913 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229289 1.00 HTT (0.73) HTTKMT2AMEN1MAPTTP53
SCHEMBL2228939 1.00 HTT (0.73) HTTKMT2AMEN1MAPTTP53
SCHEMBL2229002 1.00 HTT (0.73) HTTKMT2AMEN1MAPTTP53
SCHEMBL2230238 1.00 HTT (0.73) HTTKMT2AMEN1MAPTTP53
SCHEMBL2229224 0.98 HTT (0.70) HTTKMT2AMEN1MAPTTP53
SCHEMBL2229292 0.93 HTT (0.61) HTTKMT2AMEN1MAPTTP53
SCHEMBL2228281 0.86 HTT (0.50) HTTKMT2AMEN1MAPTTP53
Miripirium SCHEMBL3477808 0.86 HTT (1.00) HTTKMT2AMEN1MAPTTP53
SCHEMBL5298127 0.86 HTT (1.00) HTTKMT2AMEN1MAPTTP53
SCHEMBL2870371 0.86 HTT (1.00) HTTKMT2AMEN1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730157-B1 IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2011-07-27 EP disclosed
EP-1730157-A1 IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS MERCK PATENT GmbH (DE) 2006-12-13 EP disclosed
WO-2005105815-A1 IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2005-11-10 WO disclosed