Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229292 | 0.89 | HTT (0.61) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2229224 | 0.87 | HTT (0.70) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2228801 | 0.86 | HTT (0.42) | HTTCHKAMEN1KMT2AGGPS1 | |
| SCHEMBL2230238 | 0.86 | HTT (0.73) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2230433 | 0.86 | HTT (0.73) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2229002 | 0.86 | HTT (0.73) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2229289 | 0.86 | HTT (0.73) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2228939 | 0.86 | HTT (0.73) | HTTMEN1KMT2AMAPTTP53 | |
| SCHEMBL2863713 | 0.83 | HTT (0.67) | HTTCHKAMEN1KMT2AMAPT | |
| SCHEMBL2227740 | 0.81 | GGPS1 (0.51) | HTTKMT2AGGPS1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730157-B1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |