SCHEMBL223044

SCHEMBL223044

CCCCCCCCCCCCCCCCCCc1cc(C)cc(CCCCCCCCCCCC)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.55
PTGS2 P35354 7/20 0.54
ALOX5 P09917 6/20 0.54
CYP3A4 P08684 3/20 0.52
TP53 P04637 2/20 0.52
MEN1 O00255 1/20 0.52
MAPT P10636 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LIPG Q9Y5X9 1/20 0.44
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39849 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL222152 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL11777749 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL224251 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL38839 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL29135897 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL222792 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL224790 1.00 TYR (0.55) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL5078445 0.98 TYR (0.53) TYRPTGS2ALOX5CYP3A4TP53
SCHEMBL11775837 0.98 ALOX5 (0.53) TYRPTGS2ALOX5CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011855-A1 Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011867-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Outer Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed