Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304685 | 0.90 | PDE3B (0.58) | PDE3BPDE3ACTSSCTSKMAOB | |
| SCHEMBL22288923 | 0.90 | PDE3B (0.57) | PDE3BPDE3AMAOB | |
| SCHEMBL22288646 | 0.89 | PDE3B (0.52) | PDE3BPDE3ACTSSCTSKMAOB | |
| SCHEMBL22304871 | 0.89 | PDE3B (0.47) | PDE3BPDE3AS1PR1MAOB | |
| SCHEMBL22288953 | 0.88 | PDE3B (0.56) | PDE3BPDE3ACTSSCTSKMAOB | |
| SCHEMBL22288920 | 0.87 | PDE3B (0.47) | PDE3BPDE3ACTSSCTSKMAOB | |
| SCHEMBL22304679 | 0.86 | PDE3B (0.48) | PDE3BPDE3AMAOB | |
| SCHEMBL22304514 | 0.81 | MAOB (0.42) | PDE3BPDE3AMAOB | |
| SCHEMBL22288607 | 0.80 | MAOB (0.47) | PDE3BPDE3AMAOB | |
| SCHEMBL22317982 | 0.80 | PDE3B (0.52) | PDE3BPDE3AS1PR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |