Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304870 | 0.96 | PDE3B (0.41) | MAOBSYKPDE3BPDE3APRKCA | |
| SCHEMBL22288415 | 0.91 | PDE3B (0.44) | MAOBSYKPDE3BPDE3APRKCA | |
| SCHEMBL22288953 | 0.84 | PDE3B (0.56) | MAOBPDE3BPDE3A | |
| SCHEMBL22304679 | 0.82 | PDE3B (0.48) | MAOBPDE3BPDE3A | |
| SCHEMBL22288936 | 0.81 | PDE3B (0.59) | MAOBPDE3BPDE3A | |
| SCHEMBL22304512 | 0.81 | PDE3B (0.46) | MAOBPDE3BPDE3A | |
| SCHEMBL22288706 | 0.79 | MAOB (0.50) | MAOBPDE3BPDE3A | |
| SCHEMBL22288970 | 0.79 | PDE3B (0.63) | MAOBPDE3BPDE3A | |
| SCHEMBL22288636 | 0.78 | PDE3B (0.62) | MAOBPDE3BPDE3A | |
| SCHEMBL22288607 | 0.78 | MAOB (0.47) | MAOBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |