Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMO | Q99835 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | USP28 | Q96RU2 | 7/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221816 | 0.89 | MEN1 (0.61) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL2229720 | 0.87 | MAPT (0.63) | MAPTHTTBRD4CYP2C19MEN1 | |
| SCHEMBL14551116 | 0.85 | BLM (0.49) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL12515165 | 0.85 | MEN1 (0.56) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL14551119 | 0.84 | MEN1 (0.55) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL28332772 | 0.81 | USP28 (0.74) | SMOUSP28CYP2C19ALDH1A1MEN1 | |
| SCHEMBL14553227 | 0.81 | MEN1 (0.51) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL14553226 | 0.81 | MEN1 (0.51) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL12515837 | 0.80 | MEN1 (0.71) | MAPTSMOUSP28CYP2C19ALDH1A1 | |
| SCHEMBL12917026 | 0.79 | SMO (0.57) | MAPTSMOUSP28CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085261-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011085261-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. (US) | 2011-07-14 | — | — | WO | disclosed |