Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22306340 | 1.00 | EPHX1 (0.54) | EPHX1SCN4AKCNK3LMNAULK1 | |
| SCHEMBL3261012 | 0.99 | EPHX1 (0.51) | EPHX1SCN4AKCNK3LMNAULK1 | |
| SCHEMBL15428917 | 0.99 | EPHX1 (0.51) | EPHX1SCN4AKCNK3LMNAULK1 | |
| SCHEMBL2616379 | 0.99 | EPHX1 (0.51) | EPHX1SCN4AKCNK3LMNAULK1 | |
| Bromide SCHEMBL31222008 | 0.97 | SCN4A (0.50) | EPHX1SCN4AKCNK3LMNAULK1 | |
| SCHEMBL18485520 | 0.94 | SCN4A (0.56) | EPHX1SCN4AKCNK3LMNAULK1 | |
| Hydrochloric Acid SCHEMBL28152183 | 0.93 | SCN4A (0.55) | EPHX1SCN4AKCNK3LMNAPOLB | |
| SCHEMBL22305972 | 0.90 | MEN1 (0.50) | EPHX1SCN4AKCNK3LMNAPOLB | |
| SCHEMBL22305592 | 0.86 | ULK1 (0.44) | EPHX1SCN4AULK1CYP3A4CYP2D6 | |
| SCHEMBL28153112 | 0.86 | ULK1 (0.44) | EPHX1SCN4AULK1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135526-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2022-05-05 | — | — | US | disclosed |
| WO-2020156359-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学华西医院 | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135526-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SCN11A, SCN8A, SCN7A | EPHX1 4767/4885SCN4A 28/4885KCNK3 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.