Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917043 | 0.82 | NOS2 (0.39) | — | |
| SCHEMBL21253488 | 0.80 | NOS2 (0.36) | — | |
| SCHEMBL10787669 | 0.74 | — | — | |
| SCHEMBL6278869 | 0.74 | — | — | |
| SCHEMBL8166237 | 0.72 | — | — | |
| SCHEMBL22844427 | 0.70 | — | — | |
| SCHEMBL14436629 | 0.70 | — | — | |
| SCHEMBL25546984 | 0.70 | — | — | |
| SCHEMBL26137767 | 0.70 | — | — | |
| SCHEMBL7460275 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160493-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF MYOPIA | AERIE PHARMACEUTICALS, INC. (US) | 2020-08-06 | — | — | WO | disclosed |