SCHEMBL2230567

SCHEMBL2230567

CC(OC(=O)NC(CCC(=O)O)c1ccc(Cl)cc1)OC(=O)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231579 0.89 UTS2R (0.41) UTS2RKMT2A
SCHEMBL635523 0.88 KMT2A (0.41) UTS2RKMT2A
SCHEMBL637964 0.88 UTS2R (0.37) UTS2R
SCHEMBL2231578 0.86 UTS2R (0.39) UTS2RKMT2A
SCHEMBL2231639 0.85 UTS2R (0.43) UTS2RKMT2A
SCHEMBL351149 0.84 UTS2R (0.43) UTS2RKMT2A
SCHEMBL2233808 0.84 UTS2R (0.41) UTS2RKMT2A
SCHEMBL1884908 0.84 KMT2A (0.37) UTS2RKMT2A
SCHEMBL2230119 0.83 UTS2R (0.42) UTS2RKMT2A
SCHEMBL1881192 0.82 UTS2R (0.35) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2354120-A1 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XenoPort, Inc. (US) 2011-08-10 EP disclosed