SCHEMBL2233808

SCHEMBL2233808

CC(C)C(=O)OCOC(=O)NC(CCC(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 17/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351149 0.90 UTS2R (0.43) UTS2RKMT2ALMNAHTTSMN1; SMN2
SCHEMBL2231738 0.89 UTS2R (0.42) UTS2RKMT2A
SCHEMBL639252 0.88 LMNA (0.38) UTS2RLMNAHTTSMN1; SMN2
SCHEMBL2230625 0.87 UTS2R (0.40) UTS2RLMNAHTTSMN1; SMN2
SCHEMBL2231120 0.87 UTS2R (0.40) UTS2RKMT2A
SCHEMBL638666 0.85 TP53 (0.46) UTS2RKMT2ALMNAHTT
SCHEMBL2230567 0.84 UTS2R (0.40) UTS2RKMT2A
SCHEMBL636473 0.84 UTS2R (0.40) UTS2RKMT2ALMNAHTTSMN1; SMN2
SCHEMBL1884875 0.84 SMN1; SMN2 (0.39) UTS2RKMT2ALMNAHTTSMN1; SMN2
SCHEMBL2231327 0.83 UTS2R (0.47) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190657-A1 ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2017-07-06 US disclosed
EP-2354120-A1 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XenoPort, Inc. (US) 2011-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190657-A1 ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE APEH, ABAT, SI UTS2R 1572/4885KMT2A 2442/4885LMNA 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.